Note: All times listed are in Eastern Time

Friday, October 14th

There are four games tonight, but these two hold the most promise, for different reasons.

Duke at Louisville, 7PM, ESPN

The Cardinals are favored by five touchdowns. Expect them to cover thanks to Lamar Jackson continuing his Heisman campaign.

Memphis at Tulane, 8PM, ESPNU

In between highlight reel plays by Jackson, flip over to this one for a potentially more competitive contest. If the Tigers wants to keep their AAC title hopes alive - with Houston and Navy yet to come - they can’t afford a letdown against the Green Wave. Memphis is almost a two-touchdown favorite, but Tulane hasn’t lost by more than one score this season.

Saturday, October 15th

Midday

#20 West Virginia at Texas Tech, Noon, FS1

This game has the highest over/under of the weekend at 85 points. Expect a lot of offense and minimal defense. The Mountaineers are undefeated* but only two-point favorites over the 3-2 Red Raiders.

* West Virginia has only played four games so far this season.

There’s not much else to watch at noon. A trio of (bad) B1G games, listed below. In games featuring ranked opponents, NC State visits #3 Clemson, but the Tigers should win with ease; Kansas State travels to Oklahoma to face the #19 Sooners - why are they still ranked? - but neither team is good this year.

Afternoon

#1 Alabama at #9 Tennessee, 3:30PM, CBS

Tennessee’s voodoo-magic-pixie-dust-sorcery-witchcraft-mojo ran out last week as they suffered their first loss of the season in overtime against Texas A&M. However, maybe they left some back in Knoxville to use against the Crimson Tide. They’ll need some luck and then some to top Alabama, an almost two-touchdown favorite, who hasn’t lost to Tennessee since Saban came to Bama in ‘07. Then again, Alabama’s due for their annual letdown, and the Vols may be just the team to take advantage of a down game from the Tide.

#10 Nebraska at Indiana, 3:30PM, ABC/ESPN2

The Cornhuskers are 5-0, but the Hoosiers will be their toughest opponent to date. It’ll be interesting to see how Indiana bounces back after a tough loss to Ohio State. This game will likely come down to Tommy Armstrong Jr. vs. Indiana’s defense. If the Hoosiers can bottle up Armstrong, they could steal this one.

#24 Western Michigan at Akron, 3:30PM, CBSSN

The Zips pose one of Western’s biggest tests of the season. How far can the Broncos row along as an undefeated and ranked MAC team?

Nighttime

#12 Ole Miss at #22 Arkansas, 7PM, ESPN

The wackiest game of 2015 takes place again this weekend with minuscule odds of replicating the absurdity of last year. Both teams have fallen twice this season to ranked opponents. The Razorbacks are trying to salvage their year after dropping to 0-2 in the SEC following losses to #6 (then #10) Texas A&M and #1 Alabama, while the Rebels look to build a three-game losing streak after losing to #14 (then #4) Florida State and #1 Alabama as well.

#2 Ohio State at #8 Wisconsin, 8PM, ABC

With Michigan off, this is the game I’m most interested in this weekend, for reasons I don’t need to spell out. Bill Connelly boils this matchup down to Wisconsin’s success on third downs, and the last time these two teams met, the Buckeyes annihilated the Badgers 59-0. I expect a closer game on Saturday.

#Pac12AfterDark

UCLA at Washington State, 10:30PM, ESPN

The Pac-12 rarely makes any sense, and with Mike Leach on the sideline, this one has increased odds of madness.

B1G Leftovers

Minnesota at Maryland, Noon, ESPNU

Watch this if you hate the game of football.

Iowa at Purdue, Noon, ESPN2

Watch this if you hate yourself and the game of football.

Illinois at Rutgers, Noon, ESPNews

Watch this if you hate yourself, those watching with you, and the game of football.

Northwestern at Michigan State, 3:30PM, BTN

Watch this to find out who inches stumbles closer to bowl eligibility. Also, if you hate the game of football.